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Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the "Target Sign" Intern Med 58:1157-1162, Ueno, H.,et al, 2019 See this aricle in Pubmed Article Abstract We herein report the case of a 60-year-old man with a target sign in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and T1-single photon emission computed tomography showed the focal uptake in the left frontal lesion. On a brain biopsy, the patient was given a definitive diagnosis of brain metastasis from diffuse large B-cell lymphoma, and cerebral toxoplasmosis was excluded. In the present case, multilayer intensities on MRI may reflect the fast-growing nature of this tumor.

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(click to filter results - removes previous filter) lymphoma lymphoma involving CNS lymphoma,primary of CNS mimics MRI,abnormal MRI,contrast enhanced MRI,target sign neoplasm,metastatic to CNS

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